These are mainly quality of life/useful settings that you may want to consider.
When in fleets, the FC may give you a system to set as destination. By default, even loading an overview pack, Eve's route planner will not take player created jump bridges into account when planning your route. This means you're route will be different than the rest of the fleets, which may lead you to strange places in space by yourself.
You can set up autopay up to a certain amount of ISK that you will specify is acceptable so that you don't need to click “Accept” each time you use a player setup jump bridge. Press Alt-W to open up your wallet.